Researchers have found that pregnancy lipid profiles could identify women who are at risk for gestational diabetes. In women who developed the disease, a variety of conditions were noted, including lower HDL concentration, lower LDL peak diameter, and higher concentrations of small LDL particles.
Lipoprotein profiles that indicate these scenarios up to seven years before pregnancy are associated with an increased likelihood of gestational diabetes development. A causal mechanism for this relationship has not yet been identified. However, the findings are consistent with the possibility that an improvement in cardiometabolic risk profile in women of a reproductive age could reduce the risk of gestational diabetes.
This information was published in the Journal of Clinical Endocrinology & Metabolism on April 5, 2016.