Researchers recently found that people with type 2 diabetes who take diuretics may be at a significantly increased risk of amputation of a leg or foot. In fact, taking a diuretic raised the odds of amputation, or requiring a bypass or angioplasty, by 75% or more.
To draw this conclusion, outcomes were tracked for nearly 1,500 individuals with type 2 diabetes. After a seven-year follow-up, it was found that 13% of those who took a diuretic had an amputation or another procedure on their lower leg. This was compared to just 7% of participants who did not use a diuretic.
These findings were presented at the European Association for the Study of Diabetes meeting on October 1, 2018.